Propofol beyond use dating

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Physical examination revealed bilateral coarse crackles throughout both lung fields with normal heart sounds and normal neck examination.

Chest radiography showed patchy bilateral lung airspace infiltrates (Figure), which were confirmed on computed tomography angiography that was otherwise unremarkable. Chest radiography showing diffuse bilateral patchy infiltrates 60 minutes after propofol administration. Clinical characteristics of patients with propofol-associated pulmonary edema. Intravenous ceftriaxone 2 grams daily and azithromycin 500mg daily were initiated empirically, along with intravenous furosemide 40mg every six hours.

His temperature was 36.6o C, heart rate 95 beats/min, blood pressure 128/70mm Hg, respirations 18 breaths/min, and Sp O2 80%.

Supplemental oxygen through nasal cannula at four liters per minute was initiated with improvement in Sa O2 to 90%.

Common adverse effects of propofol include hypotension, respiratory depression, bradycardia and pain during injection.

To our knowledge, we report the first case of propofol-related pulmonary edema in the United States.

We report a case of a 23-year-old healthy male who developed acute cough, hemoptysis and hypoxia following administration of propofol for splinting of a foot fracture.

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It is commonly used for induction of anesthesia in the operating room, as routine sedation in the intensive care setting, and also for procedural sedation in the emergency department (ED).That risk exists in hospitals that stock verapamil injection 5 mg per 2 m L vials manufactured by Exela Pharma Sciences and naloxone injection 0.4 mg per m LMisleading acetaminophen liquid packaging could lead to acetaminophen overdoses.Caution is advised regarding labeling and packaging of acetaminophen liquid products now on store shelves at several leading chain pharmacies.The alerts are based on information submitted to the ISMP MERP.Periodically, the US Food and Drug Administration (FDA) issues alerts related to medication recalls, increased incidence of adverse events for certain medications, and recommendations for reducing naming or packaging errors.

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